![]() You might also experience other side effects, including nausea, loss of appetite, and hand trembling. When you drink grapefruit juice while taking immunosuppressants, you may face a higher risk of infection. ![]() Immunosuppressants prevent your body from rejecting transplanted organs. Some statins seem to be immune to the effects of grapefruit juice, including: If you drink grapefruit juice while using these drugs, you may experience liver and muscle damage that could lead to kidney failure. They include atorvastatin (Lipitor), lovastatin (Mevacor), and simvastatin (Zocor). Other calcium channel blockers have little to no interactions with grapefruit juice. When you drink grapefruit juice while taking these drugs, you may experience dangerous decreases in blood pressure and heart rate. Some of the most popular calcium channel blockers are nifedipine (Adalat, Procardia), nisoldipine (Sular), and felodipine (Plendil). ![]() Like beta blockers, calcium channel blockers treat cardiovascular problems. If you drink grapefruit juice while taking these drugs, they may be less effective. They include acebutolol (Sectral), celiprolol (Celicard), nadolol (Corgard), and talinolol. Beta Blockersīeta blockers treat cardiovascular problems such as high blood pressure, abnormal heart rhythms, and angina. Some antihistamines, including fexofenadine (Allegra), may not work as effectively when mixed with grapefruit juice. The most common classes of drugs that have potential interactions with grapefruit juice include: AntihistaminesĪntihistamines treat allergy symptoms. What Medications Interact With Grapefruit Juice? That means the drug may be less effective. Grapefruit juice can block these proteins and prevent your body from properly absorbing a drug. The second way involves proteins called drug transporters, which help your body absorb certain medications. The specific effects depend on the drug, your body, and how much grapefruit juice you drank. This can cause a host of adverse effects. When this enzyme is blocked, your body cannot properly metabolize certain drugs.Īs a result, the drugs will enter your blood in excess concentrations. Grapefruit juice contains compounds called furanocoumarins, which block CYP3A4. This enzyme helps metabolize (break down) drugs in your small intestine. The first and most common way involves an enzyme called cytochrome P450 3A4, or CYP3A4. Food and Drug Administration (FDA), there are two ways that grapefruit juice can interact negatively with medications. How Does Grapefruit Juice Affect Medications?Īccording to the U.S. ![]() That’s because the juice contains substances that interact negatively with many prescription and over-the-counter drugs. However, you should not drink grapefruit juice while taking certain medications. Grapefruit is a citrus fruit that contains important nutrients such as vitamin C, thiamine, and potassium. Secular Organizations For Sobriety (SOS).Eye Movement Desensitization & Reprocessing (EMDR).Drug Abuse Resources For College Students.Substance Abuse Resources For People With Disabilities.Resources For Minorities Experiencing Treatment Disparities.Complete Guide For People Facing Drug Charges.COVID-19 Mental Health And Addiction Resources.
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